Cerebroside B [88642-46-0]
Referencia TN1481-1mL
embalaje : 1mL
Marca : TargetMol
Cerebroside B
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Cerebroside B
Catalog No. TN1481Cas No. 88642-46-0
Cerebroside B1b has antiulcerogenic activity.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. Pack Size | ||
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5 mg | Backorder | |
1 mL x 10 mM (in DMSO) | Backorder |
Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
Description | Cerebroside B1b has antiulcerogenic activity. |
In vitro | Here, fusaruside is clarified biosynthetically, and its efficacy-related 10,11-double bond can be generated under the regioselective catalysis of an unprecedented α?10(E)-sphingolipid desaturase (α?10(E)-SD). α?10(E)-SD shares 17.7% amino acid sequence similarity with a C9-unmethylated α?10-sphingolipid desaturase derived from a marine diatom, and 55.7% with α?8(E)-SD from Fusarium graminearum. Heterologous expression of α?10(E)-SD in Pichia pastoris has been established to facilitate a reliable generation of 1 through the α?10(E)-SD catalyzed desaturation of Cerebroside B (2), an abundant fungal sphingolipid. Site directed mutageneses show that the conserved histidines of α?10(E)-SD are essential for the 10,11-desaturation catalysis, which is also preconditioned by the C9-methylation of the substrate. Moreover, α?10(E)-SD confers improved survival and faster growth to fungal strains at low temperature and high salinity, in parallel with to higher contents of 1 in the mycelia. |
Molecular Weight | 728.065 |
Formula | C41H77NO9 |
Cas No. | 88642-46-0 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSO
main solution, add 300 μLPEG300
mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O
mix well and clarify
Dose Conversion
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Tech Support
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Keywords
Cerebroside B