Angiotensin II type 2 receptor activation preserves megalin in the kidney and prevents proteinuria in high salt diet fed rats
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Serum Creatinine Detection Kits
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The Serum Creatinine Detection Kit quantitatively measures Creatinine levels in serum and plasma (EDTA and Heparin). This detection kit has a run time of 30 minutes. Please read the complete kit insert for more information before performing this assay. Use our provided Creatinine Standard to generate a standard curve for the assay.
Creatinine is a breakdown product of phosphocreatine (p-creatine), a molecule important for energy storage in muscles. During muscle contractions, phosphocreatine breaks down, releasing energy and forming creatinine. This conversion process, which happens non-enzymatically, allows creatinine to diffuse into the bloodstream and be excreted by the kidneys. The rate of conversion can be influenced by factors like temperature and pH.
Measuring serum creatinine is a standard method for assessing renal function. Elevated levels of creatinine in the blood usually indicate significant kidney damage. The creatinine clearance test, which takes into account factors such as age, sex, weight, and race, is a reliable indicator of kidney function. Additionally, creatinine levels can be impacted by factors such as muscle mass, diet (especially meat consumption), certain drugs, and dehydration. Therefore, understanding creatinine levels in the context of these factors is essential in medical diagnostics.
The DetectX® Serum Creatinine Detection Kit offers a precise and efficient method for determining creatinine levels in serum and plasma samples, enabling the study of renal health and evaluation of kidney function.