• Specifications

    Product Description

    ERBB2/CEN 17 CISH Probe Kit is designed for the qualitative detection of amplifications involving the human ERBB2 gene as well as the detection of chromosome 17 alpha satellites in formalin-fixed, paraffin-embedded specimens by chromogenic in situ hybridization (CISH).

    Form

    Liquid

    Recommend Usage

    The product is ready-to-use. No reconstitution, mixing, or dilution is required. Bring probe to room temperature (18-25°C) and mix briefly before use.

    Supplied Product

    Reagent Provided:

    This Probe is composed of:
    1. Digoxigenin-labeled polynucleotides, which target sequences mapping in 17q12 (chr17:37,725,661-37,973,541) harboring the ERBB2 gene region.
    2.Dinitrophenyl-labeled polynucleotides, which target sequences mapping in 17p11.1-q11.1 specific for the alpha satellite centromeric region D17Z1 of chromosome 17.
    3. Formamide based hybridization buffer.

    Probe Position

    Regulatory Status

    For research use only (RUO)

    Storage Instruction

    Store at 2-8°C in an upright position. Return to storage conditions immediately after use.

    Note

    Interpretation of the results must be made within the context of the patient´s clinical history with respect to further clinical and pathologic data of the patient by a qualified pathologist.

    Interpretation of Result

  • Applications

    Chromogenic In Situ Hybridization (FFPE Tissue)