Human Neuronal calcium binding protein (NECAB3) activation kit by CRISPRa
Referencia GA111930
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Human Neuronal calcium binding protein (NECAB3) activation kit by CRISPRa
SKU
GA111930
NECAB3 CRISPRa kit - CRISPR gene activation of human N-terminal EF-hand calcium binding protein 3
2 Weeks*
| Product Data | |
| Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
|---|---|
| Target Symbol | NECAB3 |
| Locus ID | 63941 |
| Components | GA111930G1, Neuronal calcium binding protein gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA111930G2, Neuronal calcium binding protein gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA111930G3, Neuronal calcium binding protein gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
| Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
| Reference Data | |
| RefSeq | NM_031231, NM_031232 |
| UniProt ID | Q96P71 |
| Synonyms | APBA2BP; dJ63M2.4; dJ63M2.5; EFCBP3; NIP1; STIP3; SYTIP2; XB51 |
| Summary | The protein encoded by this gene interacts with the amino-terminal domain of the neuron-specific X11-like protein (X11L), inhibits the association of X11L with amyloid precursor protein through a non-competitive mechanism, and abolishes the suppression of beta-amyloid production by X11L. This protein, together with X11L, may play an important role in the regulatory system of amyloid precursor protein metabolism and beta-amyloid generation. The protein is phosphorylated by NIMA-related expressed kinase 2, and localizes to the Golgi apparatus. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
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| SDS |
| SKU | Description | Size | ||
|---|---|---|---|---|
| KN408242 | NECAB3 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. | 1 kit | | |
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.