- More Files
- Specifications
Product Description
Goat polyclonal antibody raised against synthetic peptide of IDH1.
Immunogen
A synthetic peptide corresponding to internal region of Saccharomyces cerevisiae (S288c) IDH1.
Sequence
C-EPGSRHVGLDIKGQN
Host
Goat
Theoretical MW (kDa)
39.3
Reactivity
Yeast
Form
Liquid
Purification
Ammonium sulfate precipitation
Recommend Usage
ELISA (1:1600)
Western Blot (0.3-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Applications
Western Blot (Cell lysate)
IDH1 polyclonal antibody (Cat # PAB19472)(0.5 ug/mL) staining of S. cerevisiae lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
- Gene Info — IDH1
Entrez GeneID
855691Protein Accession#
NP_014361.1Gene Name
IDH1
Gene Alias
-
Gene Description
Idh1p
Gene Ontology
HyperlinkGene Summary
which catalyzes the oxidation of isocitrate to alpha-ketoglutarate in the TCA cycle
Other Designations
Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase, which catalyzes the oxidation of isocitrate to alpha-ketoglutarate in the TCA cycle
- Publication Reference
- mRNA decapping activators Pat1 and Dhh1 regulate transcript abundance and translation to tune cellular responses to nutrient availability.
Anil Kumar Vijjamarri, Neha Gupta, Chisom Onu, Xiao Niu, Fan Zhang, Rakesh Kumar, Zhenguo Lin, Miriam L Greenberg, Alan G Hinnebusch.
Nucleic Acids Research 2023 Jul; [Epub].
Application:WB, Yeast, dhh1 Δstrain H5217, pat1 Δstrain F2181, WT strain F2147.
- mRNA decapping activators Pat1 and Dhh1 regulate transcript abundance and translation to tune cellular responses to nutrient availability.