STRO-1 Mouse Monoclonal Antibody [Clone ID: STRO-1]

Referencia AM26067AC-N

embalaje : 100ug

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STRO-1 Mouse Monoclonal Antibody [Clone ID: STRO-1]

Specifications
Product Data
Clone Name STRO-1
Application FC
Application Flow Cytometry.
Reactivity Human
Antibody Host Mouse
Clonality Monoclonal
Immunogen Human CD34 positive bone marrow cells.
Specificity This antibody detects the cell surface antigen STRO-1 expressed by bone marrow mesenchymal stromal cells and nucleated erythroid precursors, but not by committed hematopoietic progenitors.
Buffer Tris buffered saline (TBS)
Label: APC
State: Liquid purified Ig fraction
Preservative: 15 mM Sodium Azide
Label: Conjugated with cross-linked Allophycocyanin (APC) under optimum conditions.
Concentration lot specific
Purification Size Exclusion Chromatography
Conjugation APC
Storage Store undiluted at 2-8°C.
DO NOT FREEZE!
This product is photosensitive and should be protected from light.
Stability Shelf life: one year from despatch.
Background STRO-1 is a cell surface antigen expressed by stromal elements in human bone marrow, identified by monoclonal antibody STRO-1. Approximately 10% of mononuclear cells, greater than 95% of which are nucleated erythroid precursors, are STRO-1 positive, whereas the CFU-GM (colony-forming unit granulocyte-macrophage), BFU-E (erythroid burst) and CFU-Mix (mixed colonies) committed progenitor cells are negative. CFU-F (fibroblast colony-forming cells) are present exclusively in the STRO-1 positive population. When plated under long-term bone marrow culture conditions, STRO-1 positive cells generate adherent cell layers containing multiple stromal cell types, including adipocytes, smooth muscle cells, osteoblasts, chondrocytes, and fibroblastic elements. In combination with glycophorin A, STRO-1 is a useful marker for identification of mesenchymal stem cells. STRO-1 and CD117 are markers for osteosarcoma cells.
Reference Data
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