TFR Recombinant Protein
Referencia OPCD07361-200UG
embalaje : 200ug
Marca : Aviva Systems Biology
Datasheets/Manuals | Printable datasheet for TFR Recombinant Protein (OPCD07361) |
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Predicted Species Reactivity | Homo sapiens|Human |
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Product Format | Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose. |
Host | E.coli |
Conjugation | Unconjugated |
Application | Ctrl (+), SDS-PAGE, WB |
Additional Information | Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method) |
:: | Residues: Gly567-Gly744 |
Reconstitution and Storage | 2°C to 8°C|-80°C |
Concentration | 200 ug/mL (prior to lyoph) |
Purity | > 95% |
Source | E.coli |
Tag | N-terminal His Tag |
Gene Symbol | TFRC |
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Gene Full Name | transferrin receptor |
Alias Symbols | CD71;IMD46;p90;T9;TFR;TFR1;TR;transferrin receptor protein 1;TRFR. |
NCBI Gene Id | 7037 |
Protein Name | Transferrin receptor protein 1 |
Description of Target | Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). A second ligand, the heditary hemochromatosis protein HFE, competes for binding with transferrin for an overlapping C-terminal binding site. Positively regulates T and B cell proliferation through iron uptake (PubMed:26642240). |
Uniprot ID | P02786 |
Protein Accession # | NP_001121620.1 |
Nucleotide Accession # | NM_001128148.2 |
Protein Size (# AA) | Gly567~Gly744 |
Molecular Weight | 29kDa |