TARGATT Fast & Site-Specific Transgenic Mice
Production of knock-in site-spécific mice in 3 months.
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can create site-specific knock-in mice for you with a turnaround time as fast as 3 months.
Using our novel TARGATT™ system, a gene of interest can be specifically inserted at a well-characterized, transcriptionally-active locus in the mouse genome with guaranteed transgene expression.Tissue-specific and / or ubiquitous expression options are available.
Advantages of TARGATT™ technology:
Site-specific DNA integration (knockin) in transcriptionally-active locus
- Ensures robust gene expression
- Eliminates unpredictable phenotypes caused by random integration
- Allows for proper comparison of different transgenes
Single-copy integration
- Eliminates repeat-induced gene silencing and genomic instability.
Insertion of intact transgene
- Avoids broken transgenes with unexpected phenotype
High integration efficiency
