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ApexBio es un proveedor líder de péptidos y reactivos de laboratorio para la investigación biológica. ApexBio cuenta con una amplia línea de productos en áreas de investigación como la apoptosis, la epigenética, la biología del cáncer, etc. ApexBio también ofrece servicios personalizados que incluyen la síntesis de péptidos, la producción de anticuerpos y el desarrollo de ensayos. | ||
Phytopathology reagents - Polymyxin B
Polymyxin B is a member of the polymyxin group of antibiotics, obtained from different strains of Bacillus polymyxa and related species.
Polymyxin B is used for infections with gram-negative organisms, but may be neurotoxic and nephrotoxic. All gram-positive bacteria, fungi, and the gram-negative cocci, are resistant.
Polymixin B acts against microorganisms by binding to and interfering with the permeability of the cytoplasmic membrane. After binding to lipopolysaccharide (LPS) in the outer membrane of Gram-negative bacteria, polymyxins disrupt both the outer and inner membranes. The hydrophobic tail is important in causing membrane damage, suggesting a detergent-like mode of action.
Polymixin B can be used with a basal medium and additional antibiotics to select specific microorganisms like Acidovorax avenae and Ralstonia solanacearum for phytopathology.
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