Angene
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Angene se compromete a proporcionar productos químicos de calidad para su uso en investigación y desarrollo y fabricación comercial. Angene ofrece más de 100.000 productos, incluidos reactivos de laboratorio, bloques de construcción, intermediarios, productos básicos a granel, productos agroquímicos, ingredientes naturales e ingredientes farmacéuticos activos (API). Además de los más de 100.000 productos, Angene ofrece síntesis personalizadas de productos químicos que no están disponibles comercialmente.
Página web: www.angenechemical.com
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Reducing agent - DTT
Dithiothreitol (DTT) is a small redox molecule, also known as Cleland's reagent. Its raw chemical formula is C4H10O2S2. Its reducing power on thiols makes it a reagent widely used in biochemistry to prevent the oxidation of cysteines in proteins.
DTT is a strong reducing agent whose effectiveness results from its propensity to form a six-atom ring with an internal disulfide bridge. It is used to stabilize enzymes and other proteins with free sulfhydryl groups.
DTT is mainly used to reduce protein disulfide bridges and, more generally, to prevent the formation of intramolecular and intermolecular disulfide bridges. However, DTT cannot reduce buried disulfide bridges (inaccessible to the solvent) unless denaturing conditions are used. DTT is a reducing agent almost 7 times more powerful than βME (β-mercaptoethanol) and does not have the repulsive odor or toxicity disadvantages of βME.
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