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BioWorld proporciona una variedad de productos y servicios para las industrias de Ciencias de la Vida y Biotecnología. Ofrecemos herramientas moleculares, reactivos biológicos y suministros de laboratorio de alta calidad para laboratorios analíticos, instituciones educativas y de investigación de todo el mundo. BioWorld se centra en reactivos de bioafinidad para la purificación de proteínas y la investigación proteómica. Disponemos de una amplia gama de proteínas recombinantes y péptidos sintéticos.
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Jacalin lectin (Artocarpus integrifolia) (AIA)
Jacalin lectin (AIA) is isolated from jackfruit seeds (Artocarpus integrifolia). The lectin belongs to the family of galactose-binding lectins and has a tetrameric two-chain structure with a weight of 66 kDa. Lectins are, due to their specific binding to carbohydrate structures on the cell surface or elsewhere useful in haematology, immunology or as specific markers for membrane glycoprotein structures.
Jacalin is preferably used in applications to isolate IgA from human serum, isolating human plasma glycoproteins and for applications in histochemistry. The lectin is blood group non-specific after neuraminidase treatment and agglutinates human erythrocytes at a concentration of >7,8µg/mL. A post-translational proteolytic modification of Jacalin gives the lectin a novel carbohydrate-binding site involving the N terminus of the a-chain. The relative affinities of the lectin for galactose derivatives, as well as the structural basis of its T-antigen specificity, are explained by its protein structure.
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RUOCE / IVD
- Agarose 15
- FITC 5
- TRITC 5
- Texas Red® 5
- Biotin 4
- AP 3
- Cy5 3
- Ferritin 3
- Beads 2
- HRP 2
- Cy3 1
- DyLight 488 1
- Gold 1
- Lectins
- plant 54
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