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BioWorld proporciona una variedad de productos y servicios para las industrias de Ciencias de la Vida y Biotecnología. Ofrecemos herramientas moleculares, reactivos biológicos y suministros de laboratorio de alta calidad para laboratorios analíticos, instituciones educativas y de investigación de todo el mundo. BioWorld se centra en reactivos de bioafinidad para la purificación de proteínas y la investigación proteómica. Disponemos de una amplia gama de proteínas recombinantes y péptidos sintéticos.
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Concanavalin A (Jackbean) (Con A)
Concanavalin A (Con A), a mannose/glucose-binding lectin isolated from Jack beans (Canavalia ensiformis), is a well-known T cell mitogen that can activate the immune system, recruit lymphocytes and elicit cytokine production. In addition to its mitogenic activity, ConA can induce programmed cell death via mitochondria-mediated apoptosis and autophagy. Interestingly, ConA has been reported to activate NFAT (nuclear factor of activated T cells), a family of transcription factors that are important in the development and function of the immune system, including T cell receptor (TCR) engagement. Specifically, binding of ConA triggers cross-linking of the TCR complex leading to T cell activation.
Concanavalin A (Con A) has 4 subunits and a molecular weight of 104 kDa. Con A is the most widely used lectin and has broad applicability. For example, immobilized Con A has been used in affinity chromatography purifications of a wide variety of glycoproteins and cellular structures.
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RUOCE / IVD
- Agarose 23
- FITC 9
- Beads 8
- Texas Red® 8
- TRITC 5
- DyLight 488 4
- Biotin 3
- Cy5 3
- Ferritin 3
- AP 2
- Cy3 2
- Gold 2
- HRP 2
- Lectins
- plant 82
- fungus 2
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