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BioWorld proporciona una variedad de productos y servicios para las industrias de Ciencias de la Vida y Biotecnología. Ofrecemos herramientas moleculares, reactivos biológicos y suministros de laboratorio de alta calidad para laboratorios analíticos, instituciones educativas y de investigación de todo el mundo. BioWorld se centra en reactivos de bioafinidad para la purificación de proteínas y la investigación proteómica. Disponemos de una amplia gama de proteínas recombinantes y péptidos sintéticos.
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Galanthus nivalis Lectin (GNL/GNA)
Galanthus nivalis lectin or agglutinin (GNL/GNA) is isolated from snowdrop bulbs. GNL consists of four identical subunits with a molecular weight of 50,000 and an isoelectric point between pH 3.5 and pH 4.0. Galanthus nivalis lectin, unlike most mannose-specific lectins, is not a metalloprotein and does not require Ca++or Mn++ for binding.
This lectin is known to agglutinate rabbit erythrocytes but not human erythrocytes. GNL contains little to no carbohydrate and specifically binds to murine IgM immunoglobin and human beta2-macroglobulin, but not to alpha-linked glucose (unlike majority of mannose-binding lectins). Structures containing (beta-1,3) mannose residues are preferred for binding and elutes with the sugar Mannose. GNL is useful for HIV research, applicable for blood cell agglutination studies, and has set a model system to help understand the molecular basis of how proteins recognize carbohydrates.
GLN is used for blood cell agglutination studies, HIV research, virus isolation, mouse IgM isolation.
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- Agarose 4
- Cy5 2
- DyLight 488 2
- HRP 2
- AP 1
- Biotin 1
- Cy3 1
- FITC 1
- Ferritin 1
- Gold 1
- TRITC 1
- Texas Red® 1
- Lectins
- plant 20
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