Reactivos e instrumentos para inmunología, biología celular y biología molecular.

Anti-BAF53b Antibody FL650 Conjugate

Imprimir

Referencia 75-311-FL650

embalaje : 200uL

Contact local distributor :

Teléfono : +1 850 650 7790

Marca : Antibodies Incorporated

Solicitar más información

Contact local distributor :

Teléfono : +1 850 650 7790

SKU: 75-311-FL650

Product Details

Target

BAF53b

Target Description

Actin Like 6B, of BAFcomplex 53 KDa Subunit (BAF53b) is encoded by the gene ACTL6B and is a member of actin-related proteins family. It is a subunit of the neuron specific chromatin remodeling complex (nBAF complex). ACTL6B plays a role in remodeling mononucleosomes in an ATP-dependent fashion, and is required for postmitotic neural development and dendritic outgrowth. Diseases associated with ACTL6B include Early Infantile Epileptic Encephalopathy 76 and Intellectual Developmental Disorder with Severe Speech and Ambulation Defects.

Format

Purified by Protein A chromatography

Concentration

0.5 mg/mL

Clonality

Monoclonal

Clone

N332B/15

Isotype

IgG1

Applications

ICC, IHC

Host Species

Mouse

Gene Name

ACTL6B ACTL6 BAF53B

Molecular Weight

53 kDa

Antigen

Fusion protein amino acids 39-114 (TTVGLLAAEEGGGLELEGDKEKKGKIFHIDTNALHVPRDGAEVMSPLKNGMIEDWECFRAILDHTYSKHVKSEPNL, actin subdomain 2) of human BAF53b (accession number O94805) produced recombinantly in E. Coli

Species Reactivity

Human, Mouse

Antibody Registry ID

AB_2940087

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL650 Ex: 655 nm, Em: 676 nm

Specificity

Does not cross-react with BAF53a

Quality Control

Each new lot of antibody is quality control tested by IHC on either rat or mouse brain and confirmed to give the expected staining pattern.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

Actin-like protein 6B (53 kDa BRG1-associated factor B) (Actin-related protein Baf53b) (ArpNalpha) (BRG1-associated factor 53B) (BAF53B)

UniProt Details

UniProt (Human): O94805
UniProt (Immunogen Species): O94805

Anti-BAF53b Antibody FL650 Conjugate

Referencia 75-311-FL650

Contact local distributor :

Marca : Antibodies Incorporated

Contact local distributor :

SKU: 75-311-FL650

Product Details

Bulk Order Anti-BAF53b Antibody FL650 Conjugate