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> Corn oil [8001-30-7]

Corn oil [8001-30-7]

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Corn oil, extracted from the germ of corn, can be used as a carrier for agent molecules.

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Corn oil Estructura química

Corn oil Estructura química

No. CAS : 8001-30-7

This product is a controlled substance and not for sale in your territory.

Based on 67 publication(s) in Google Scholar

Descripciòn

Corn oil, extracted from the germ of corn, can be used as a carrier for agent molecules.

In Vivo

Corn oil-gavaged rats have 54% lower serum growth hormone (GH) levels, and replacement of GH into corn oil-gavaged rats by osmotic minipump infusion increase in situ MNCL cell proliferation to rates observed in water-gavaged animals[1].
Corn oil is commonly used as a feed additive or a delivery vehicle for lipophilic substances In an animal research setting[3].
Corn oil can become contaminated, and cause death/systemic infections several days after IP injections, so corn oil should be aliquoted and frozen (recommendation); thaw and make fresh solution each time.
Corn oil is more recommended for gavage administration[4].
Intraperitoneal oil application causes local inflammation with depletion of resident peritoneal macrophages[5].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Female C57BL/6J mice (n = 90; age, 6 to 7 wk)[3]
Dosage: 0.1 mL.
Administration: Intraperitoneal injection every 48 h for a total of 4 injections over a 7-d period.
Result: At day 21, pharmaceutical-grade (PG) corn oil had a significantly higher pathology score compared with nonpharmaceutical-grade corn oil. No other significant differences between the corn oil groups were observed. The use of nonpharmaceutical grade corn oil did not result in adverse clinical consequences and is presumed safe to use for intraperitoneal injection in mice.
No. CAS

8001-30-7
Appearance

Liquid (Density: 0.90 g/cm3)

Color

Colorless to light yellow

SMILES

[Corn oil]
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvente y solubilidad
In Vitro: 

Ethanol : 10 mg/mL (Need ultrasonic)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Pureza y Documentación

SDS (393 KB)

COA (243 KB)

Instrucciones de manejo (2659 KB)
Referencias

  • [1]. Hursting SD, et al. Inhibition of rat mononuclear cell leukemia by corn oil gavage: in vivo, in situ and immune competence studies. Carcinogenesis. 1994 Feb;15(2):193-9.  [Content Brief]

    [2]. Gilbertson JR, et al. Inhibition of growth of Morris hepatomas 7777 and 7800 by corn oil. Oncology. 1977;34(2):62-4.  [Content Brief]

    [3]. Jennifer S Hubbard, et al. Effects of Repeated Intraperitoneal Injection of Pharmaceutical-grade and Nonpharmaceutical-grade Corn Oil in Female C57BL/6J Mice. J Am Assoc Lab Anim Sci. 2017 Nov 1;56(6):779-785.  [Content Brief]

    [4]. Administration Of Drugs and Experimental Compounds in Mice and Rats

    [5]. Elisenda Alsina-Sanchis, et al. Intraperitoneal Oil Application Causes Local Inflammation with Depletion of Resident Peritoneal Macrophages. Mol Cancer Res. 2021 Feb;19(2):288-300.  [Content Brief]

  • [1]. Hursting SD, et al. Inhibition of rat mononuclear cell leukemia by corn oil gavage: in vivo, in situ and immune competence studies. Carcinogenesis. 1994 Feb;15(2):193-9.

    [2]. Gilbertson JR, et al. Inhibition of growth of Morris hepatomas 7777 and 7800 by corn oil. Oncology. 1977;34(2):62-4.

    [3]. Jennifer S Hubbard, et al. Effects of Repeated Intraperitoneal Injection of Pharmaceutical-grade and Nonpharmaceutical-grade Corn Oil in Female C57BL/6J Mice. J Am Assoc Lab Anim Sci. 2017 Nov 1;56(6):779-785.

    [4]. Administration Of Drugs and Experimental Compounds in Mice and Rats

    [5]. Elisenda Alsina-Sanchis, et al. Intraperitoneal Oil Application Causes Local Inflammation with Depletion of Resident Peritoneal Macrophages. Mol Cancer Res. 2021 Feb;19(2):288-300.

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Corn oil Related Classifications

  • Others
  • Others
  • Biochemical Assay Reagents
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Corn oil8001-30-7Biochemical Assay ReagentsInhibitorinhibitorinhibit

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T5137-100mL
Corn oil [8001-30-7]
 100mL