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- Specifications
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of CRHR1.
Immunogen
A synthetic peptide corresponding to 18 amino acids at extracellular domain of human CRHR1.
Host
Rabbit
Reactivity
Bovine, Dog, Hamster, Horse, Human, Monkey, Pig, Sheep
Specificity
BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Form
Liquid
Purification
Immunoaffinity chromatography
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (20 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -80°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human pituitary with CRHR1 polyclonal antibody (Cat # PAB26156).
Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. - Gene Info — CRHR1
Entrez GeneID
1394Protein Accession#
P34998Gene Name
CRHR1
Gene Alias
CRF-R, CRF1, CRFR1, CRH-R1h, CRHR, CRHR1f
Gene Description
corticotropin releasing hormone receptor 1
Omim ID
122561Gene Ontology
HyperlinkGene Summary
This gene encodes a G-protein coupled receptor that binds neuropeptides of the corticotropin releasing hormone family that are major regulators of the hypothalamic-pituitary-adrenal pathway. The encoded protein is essential for the activation of signal transduction pathways that regulate diverse physiological processes including stress, reproduction, immune response and obesity. Alternative splicing results in multiple transcript variants
Other Designations
CRF1 receptor isoform I variant B|corticotropin releasing hormone receptor variant 1h|corticotropin-releasing factor receptor|seven transmembrane helix receptor
- Interactomes
- Pathways
- Diseases