CX3CR1 Mouse Monoclonal Antibody [Clone ID: 1G4]
Referencia AM26731PU-N
embalaje : 100ug
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| Product Data | |
| Clone Name | 1G4 |
|---|---|
| Application | IHC |
| Application | Immunohistochemistry on Paraffin Sections: 2 µg/ml (1/100), pretreatment with proteinase K required. Suggested Positive Control: Human brain cortex. |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG2b |
| Clonality | Monoclonal |
| Immunogen | DNA vaccine |
| Specificity | This antibody detetcs CX3C Receptor 1. The specificity of the antibody was verified by flow cytometry with cells expressing the recombinant protein. The epitope has not been further characterized. |
| Buffer | Phosphate buffered saline pH 7.2 (PBS) State: Purified State: Lyophilized purified IgG fraction from Serum-Free Cell Culture Supernatant Stabilizer: 5 mg/ml BSA Preservative: 0.1% Kathon |
| Reconstitution Method | Restore by adding 0.5 ml distilled water. |
| Concentration | 0.2 mg/ml (after reconstitution) |
| Purification | Affinity Chromatography on Protein G |
| Conjugation | Unconjugated |
| Storage | Store lyophilized at 2-8°C for 6 months or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Gene Name | C-X3-C motif chemokine receptor 1 |
| Database Link | |
| Background | G-protein coupled receptor 1 3 (GPR13) is a 355 amino acid protein that belongs to the G - protein coupled receptor 1 family. Biologically, the fractalkine (CX3CL1) to fractalkine receptor (CX3CR1) interactions play an important role in macrophage recruitment to target organs such as the brain, the intestine, the liver or the lungs. Accordingly, expression of the CX3CR1 has been described in inflammation - and tumor - associated macrophages, intestinal lamina propia macrophages, and B cells. Also, CX3CR1 mediates adhesive and migratory functions and acts as a coreceptor with CD4 for HIV - 1 virus gp160 envelope protein. |
| Synonyms | CX3C chemokine receptor 1, C-X3-C CKR-1,CMKBRL1, CMK-BRL-1 |
| Reference Data | |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.