Human Sphingosine 1 phosphate phosphatase 2 (SGPP2) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SGPP2
Locus ID	130367
Kit Components	GA115110G1, Sphingosine 1 phosphate phosphatase 2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA115110G2, Sphingosine 1 phosphate phosphatase 2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA115110G3, Sphingosine 1 phosphate phosphatase 2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001320833, NM_001320834, NM_152386
UniProt ID	Q8IWX5
Synonyms	SPP2; SPPase2
Summary	The protein encoded by this gene is a transmembrane protein that degrades the bioactive signaling molecule sphingosine 1-phosphate. The encoded protein is induced during inflammatory responses and has been shown to be downregulated by the microRNA-31 tumor suppressor. Alternative splice variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2016]