Mouse Anti-Human CD13-UNLB

Referencia 9556-01

embalaje : 0.1mg

Marca : Southern Biotech

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Teléfono : +1 850 650 7790

More Information
Clone 22A5
Isotype Mouse (BALB/c) IgG2aκ
Isotype Control Mouse IgG2a-UNLB (HOPC-1)
Specificity Human CD13
Alternative Names gp150, aminopeptidase N, APN, ANPEP
Description CD13, also known as aminopeptidase N, is a 150 kDa type II integral membrane glycoprotein. It is expressed on granulocytes, monocytes and their precursors, and on mast cells. CD13 is a zinc-binding metalloprotease that is involved in cell surface antigen presentation via its digestion of many MHC-bound regulatory peptides.
Immunogen Osteoclasts from osteoclastomas
Conjugate UNLB (Unconjugated)
Buffer Formulation Borate buffered saline, pH 8.2
Clonality Monoclonal
Concentration 0.1 mg/mL
Volume 1.0 mL
Recommended Storage 2-8°C
Applications Flow Cytometry – Quality tested 3,4
Immunohistochemistry-Frozen Sections – Reported in literature 1-3
Immunoprecipitation – Reported in literature 5

RRID Number AB_2796921
Gene ID 290 (Human)
Gene ID Symbol ANPEP (Human)
Gene ID Aliases APN; CD13; GP150; LAP1; P150; PEPN
UniProt ID P15144 (Human
UniProt Name AMPN_HUMAN (Human)
Documentation
Technical Bulletin Safety Datasheet

Certificate of Analysis Lookup

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  1. 1. Horton MA, Lewis D, McNulty K, Pringle JA, Chambers TJ. Monoclonal antibodies to osteoclastomas (giant cell bone tumors): definition of osteoclast-specific cellular antigens. Cancer Res. 1985;45:5663-9. (Immunogen, IHC-FS)
  2. 2. Angelotti ML, Ronconi E, Ballerini L, Peired A, Mazzinghi B, Sagrinati C, et al. Characterization of renal progenitors committed toward tubular lineage and their regenerative potential in renal tubular injury. Stem Cells. 2012;30:1714-25. (IHC-FS)
  3. 3. Saho T, Kishida T, Hirano H, Hashikawa T, Shimabukuro Y, Murakami S. Induction of CD13 on T-lymphocytes by adhesive interaction with gingival fibroblasts. J Dent Res. 2003;82:893-8. (IHC-FS, FC)
  4. 4. Ashmun RA, Shapiro LH, Look T. Deletion of the zinc-binding motif of CD13/aminopeptidase N molecules results in loss of epitopes that mediate binding of inhibitory antibodies. Blood. 1992;79:3344-9. (FC)
  5. 5. Personal communication (IP)