Mouse Pltp activation kit by CRISPRa
Referencia GA203297
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Mouse Pltp activation kit by CRISPRa
SKU
GA203297
Pltp CRISPRa kit - CRISPR gene activation of mouse phospholipid transfer protein
2 Weeks*
| Product Data | |
| Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
|---|---|
| Target Symbol | Pltp |
| Locus ID | 18830 |
| Components | GA203297G1, Pltp gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA203297G2, Pltp gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA203297G3, Pltp gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
| Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
| Reference Data | |
| RefSeq | NM_011125 |
| UniProt ID | P55065 |
| Synonyms | Bpife; OD107 |
| Summary | Facilitates the transfer of a spectrum of different lipid molecules, including diacylglycerol, phosphatidic acid, sphingomyelin, phosphatidylcholine, phosphatidylglycerol, cerebroside and phosphatidyl ethanolamine. Essential for the transfer of excess surface lipids from triglyceride-rich lipoproteins to HDL, thereby facilitating the formation of smaller lipoprotein remnants, contributing to the formation of LDL, and assisting in the maturation of HDL particles. PLTP also plays a key role in the uptake of cholesterol from peripheral cells and tissues that is subsequently transported to the liver for degradation and excretion. Two distinct forms of PLTP exist in plasma: an active form that can transfer PC from phospholipid vesicles to high-density lipoproteins (HDL), and an inactive form that lacks this capability (By similarity).[UniProtKB/Swiss-Prot Function] |
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| SDS |
| SKU | Description | Size | ||
|---|---|---|---|---|
| KN513496 | Pltp - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. | 1 kit | | |
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.