Proteinase K (Highly Pure)

Proteinase K (Highly Pure)
Catalog number: B2012630
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 500 U
Molecular Weight or Concentration: > 500 U/mL
Supplied as: Solution
Applications: molecular tool for various biochemical applications
Storage: 2-8°C
Keywords: ProK, native proteinase K solution, non-specific protease
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Kushnirov VV, Dergalev AA, Alexandrov AI. Proteinase K resistant cores of prions and amyloids Prion. 2020 Dec;14(1):11-19.
2: Silva CJ, Vázquez-Fernández E, Onisko B, Requena JR. Proteinase K and the structure of PrPSc: The good, the bad and the ugly Virus Res. 2015 Sep 2;207:120-6.
3: Paudyal S, Sigdel G, Shah SK, Sharma SK, Grubb JD, Micic M, Caseli L, Leblanc RM. Interfacial behavior of Proteinase_K enzyme at air-saline subphase J Colloid Interface Sci. 2022 Jun 15;616:701-708.
4: Brilhante RSN, Lopes RGP, de Aguiar L, de Oliveira JS, Araújo GDS, Paixão GC, Pereira-Neto WA, Freire RS, Nunes JVS, de Lima RP, Santos FA, Sidrim JJC, Rocha MFG. Inhibitory effect of proteinase K against dermatophyte biofilms: an alternative for increasing the antifungal effects of terbinafine and griseofulvin Biofouling. 2022 Mar;38(3):286-297.
5: Xu C, Battig A, Schartel B, Siegel R, Senker J, von der Forst I, Unverzagt C, Agarwal S, Möglich A, Greiner A. Investigation of the Thermal Stability of Proteinase_K for the Melt Processing of Poly(l-lactide) Biomacromolecules. 2022 Nov 14;23(11):4841-4850.
6: Gulmez C, Altinkaynak C, Özdemir N, Atakisi O. Proteinase_K hybrid nanoflowers (P-hNFs) as a novel nanobiocatalytic detergent additive Int J Biol Macromol. 2018 Nov;119:803-810.
7: Fränzel B, Fischer F, Steegborn C, Wolters DA. Proteinase_K improves quantitative acylation studies Proteomics. 2015 Jan;15(1):44-7.
8: Shukla A, Gangwar M, Sharma G, Prakash P, Nath G. Vitality of Proteinase K in rRTPCR Detection of SARS-CoV2 Bypassing RNA Extraction Front Cell Infect Microbiol. 2021 Nov 3;11:717068.
9: Yoshinaga S, Yamanaka T, Miyazaki H, Okuzumi A, Hiyama A, Murayama S, Nukina N. Preserved proteinase_K-resistant core after amplification of alpha-synuclein aggregates: Implication to disease-related structural study Biochem Biophys Res Commun. 2020 Feb 12;522(3):655-661.
10: Kim YC, Won SY, Jeong MJ, Jeong BH. Absence of proteinase K-resistant PrP in Korean Holstein cattle carrying potential bovine spongiform encephalopathy-related E211K somatic mutation Transbound Emerg Dis. 2022 Mar;69(2):805-812.

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