RAB13 Human shRNA Plasmid Kit (Locus ID 5872)
Referencia TL315508
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| Product Data | |
| Locus ID | 5872 |
|---|---|
| Synonyms | GIG4 |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Format | Lentiviral plasmids |
| Components | RAB13 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 5872). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | NM_001272038, NM_002870, NR_073553, NM_002870.2, NM_002870.3, NM_001272038.1, BC000799, BC000799.1, BC009227, BC073168, BC094846, NM_002870.5 |
| UniProt ID | P51153 |
| Summary | This gene is a member of the Rab family of small G proteins and plays a role in regulating membrane trafficking between trans-Golgi network (TGN) and recycling endosomes (RE). The encoded protein is involved in the assembly of tight junctions, which are components of the apical junctional complex (AJC) of epithelial cells. The AJC plays a role in forming a barrier between luminal contents and the underlying tissue. Additional functions associated with the protein include endocytic recycling of occludin, regulation of epithelial cell scattering, neuronal regeneration and regulation of neurite outgrowth. Alternately spliced transcript variants have been observed for this gene. A pseudogene associated with this gene is located on chromosome 12. [provided by RefSeq, Jan 2013] |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact tech@clinisciences.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
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