- More Files
The standard curve is for the purpose of illustration only and should not be used to calculate unknowns. A standard curve should be generated each time the assay is performed.
- Specifications
Product Description
TNFRSF11B (Human) ELISA Kit is a biotin labelled antibody based sandwich enzyme immunoassay for the quantitative measurement of human osteoprotegerin in serum, plasma, synovial fluid and tissue culture medium.
Suitable Sample
Plasma (Citrate, EDTA, Heparin), Serum
Sample Volume
100 uL
Label
HRP-conjugate
Detection Method
Colorimetric
Assay Type
Quantitative
Intra-Assay
4.50%
Inter-Assay
5.50%
Spiking Recovery
94.60%
Calibration Range
1.5 to 60 pmol/L
Limit of Detection
0.03 pmol/L
Reactivity
Human, Monkey
Regulation Status
For research use only (RUO)
Quality Control Testing
Standard curve
The standard curve is for the purpose of illustration only and should not be used to calculate unknowns. A standard curve should be generated each time the assay is performed.
Storage Instruction
Store the kit at 4°C.
- Applications
Quantification
- Gene Info — TNFRSF11B
Entrez GeneID
4982Gene Name
TNFRSF11B
Gene Alias
MGC29565, OCIF, OPG, TR1
Gene Description
tumor necrosis factor receptor superfamily, member 11b
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined. [provided by RefSeq
Other Designations
osteoclastogenesis inhibitory factor|osteoprotegerin
- Interactomes
- Pathways
- Diseases
- Acute Disease
- Alveolar Bone Loss
- Alzheimer disease
- Arthritis
- Asthma
- Body Weight
- Bone Diseases
- Brain Ischemia
- Calcinosis
+ View More Disease
- Publication Reference
- Hormone concentrations throughout uncomplicated pregnancies: a longitudinal study.
Schock H, Zeleniuch-Jacquotte A, Lundin E, Grankvist K, Lakso HA, Idahl A, Lehtinen M, Surcel HM, Fortner RT.
BMC Pregnancy and Childbirth 2016 Jul; 16(1):146.
Application：ELISA, Human, Serum.
- Hormone concentrations throughout uncomplicated pregnancies: a longitudinal study.