Acalabrutinib
Cat# 440755-5mg
Size : 5mg
Marca : US Biological
440755 Acalabrutinib
Clone Type
PolyclonalGrade
Highly PurifiedShipping Temp
RTStorage Temp
4°CAcalabrutinib, is an experimental anti-cancer drug and a selective Bruton's tyrosine kinase (BTK) inhibitor. This kinase transmits signals from B-cell Receptor (BCR), and thus any genetic BTK mutation causes B-Cell immunodeficiency. Therefore, BTK inhibitors targeting B-cell signaling has shown great promise for the treatment of chronic lymphocytic leukemia (CLL).||Synonyms:|4-[8-amino-3-[(2S)-1-(1-oxo-2-butyn-1-yl)-2-pyrrolidinyl]imidazo[1,5-a]pyrazin-1- yl]-N-2-pyridinylbenzamide; ACP 196||CAS No:|1420477-60-6||Molecular Formula:|C26H23N7O2||Molecular Weight:|465.51||Purity (HPLC):|≥98%||Appearance:|Light yellow to yellow solid||Solubility:|DMSO (Slightly), Methanol (Slightly)||NMR, CNMR, LC-MS:|Conforms to reference||Storage and Stability:|May be stored at RT for short-term only. Long-term storage is recommended at 4°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.