Images
Immunocytochemistry
Application

Immunocytochemistry

Immunocytochemical staining of SK-N-BE with ANK2 monoclonal antibody, clone S105-13 (ATTO 488) (Cat # MAB18243). (A) DAPI (blue) nuclear stain (B) Phalloidin Texas Red F-Actin stain (C) ANK2 Antibody and (D) Composite.

  • Specifications

    Product Description

    Mouse monoclonal antibody raised against synthetic peptide of human ANK2.

    Immunogen

    A synthetic peptide corresponding to amino acids 203-496 of human ANK2.

    Host

    Mouse

    Reactivity

    Human

    Form

    Liquid

    Conjugation

    ATTO 488

    Purification

    Protein G Purification

    Isotype

    IgG1

    Recommend Usage

    Immunocytochemistry (1:200)
    Immunofluorescence (1:200)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:200)
    Western Blot (1:1000)
    The optimal working dilution should be determined by the end user.

    Storage Buffer

    In PBS, pH 7.4 (50% glycerol, 0.09% sodium azide).

    Storage Instruction

    Store at -20°C.

    Note

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

  • Applications

    Western Blot

    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)

    Immunocytochemistry

    Immunocytochemical staining of SK-N-BE with ANK2 monoclonal antibody, clone S105-13 (ATTO 488) (Cat # MAB18243). (A) DAPI (blue) nuclear stain (B) Phalloidin Texas Red F-Actin stain (C) ANK2 Antibody and (D) Composite.

    Immunofluorescence

  • Gene Info — ANK2

    Entrez GeneID

    287

    Protein Accession#

    Q01484

    Gene Name

    ANK2

    Gene Alias

    DKFZp686M09125, DKFZp686P0948, FLJ38277, LQT4

    Gene Description

    ankyrin 2, neuronal

    Omim ID

    106410 600919

    Gene Ontology

    Hyperlink

    Gene Summary

    This gene encodes a member of the ankyrin family of proteins that link the integral membrane proteins to the underlying spectrin-actin cytoskeleton. Ankyrins play key roles in activities such as cell motility, activation, proliferation, contact and the maintenance of specialized membrane domains. Most ankyrins are typically composed of three structural domains: an amino-terminal domain containing multiple ankyrin repeats; a central region with a highly conserved spectrin binding domain; and a carboxy-terminal regulatory domain which is the least conserved and subject to variation. The protein encoded by this gene is required for targeting and stability of Na/Ca exchanger 1 in cardiomyocytes. Mutations in this gene cause long QT syndrome 4. Multiple transcript variants encoding different isoforms have been described. [provided by RefSeq

    Other Designations

    OTTHUMP00000163834|ankyrin 2|ankyrin B|ankyrin, brain|ankyrin, nonerythroid|ankyrin-2, nonerythrocytic|brank-2

  • Interactomes
  • Diseases