General Info
| Host: | Rat |
| Applications: | FC |
| Reactivity: | Mouse |
| Note: | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
| Short Description: | Rat monoclonal antibody anti-Low affinity immunoglobulin epsilon Fc receptor is suitable for use in Flow Cytometry research applications. |
| Clonality: | Monoclonal |
| Clone ID: | B3B4 |
| Conjugation: | APC |
| Isotype: | IgG2ak |
| Formulation: | PBS with 0.05% Proclin300, 1% BSA |
| Concentration: | 0.2 mg/mL |
| Storage Instruction: | Recommend storing between 2-8°C and protecting from prolonged exposure to light. Do not freeze this product. |
Information
| Gene Symbol: | Fcer2 |
| Gene ID: | 14128 |
| Uniprot ID: | FCER2_MOUSE |
Description
| Post Translational Modifications | N- and O-glycosylated. |
| Function | Low-affinity receptor for immunoglobulin E (IgE) and CR2/CD21. Has essential roles in the regulation of IgE production and in the differentiation of B cells. On B cells, initiates IgE-dependent antigen uptake and presentation to T cells. On macrophages, upon IgE binding and antigen cross-linking induces intracellular killing of parasites through activation of L-Arginine-nitric oxide pathway. |
| Protein Name | Low Affinity Immunoglobulin Epsilon Fc ReceptorFc-Epsilon-RiiLymphocyte Ige ReceptorCd Antigen Cd23 |
| Cellular Localisation | Cell MembraneSingle-Pass Type Ii Membrane ProteinLipid-Anchor |
| Alternative Antibody Names | Anti-Low Affinity Immunoglobulin Epsilon Fc Receptor antibodyAnti-Fc-Epsilon-Rii antibodyAnti-Lymphocyte Ige Receptor antibodyAnti-Cd Antigen Cd23 antibodyAnti-Fcer2 antibodyAnti-Fcer2a antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance