General Info
| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Monkey |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit polyclonal antibody anti-Cleaved-Matrix metalloproteinase-15-Y132 (113-162 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000ELISA 1:10000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Information
| Gene Symbol: | MMP15 |
| Gene ID: | 4324 |
| Uniprot ID: | MMP15_HUMAN |
| Immunogen Region: | 113-162 aa |
| Specificity: | Cleaved-MMP-15 (Y132) Polyclonal Antibody detects endogenous levels of fragment of activated MMP-15 protein resulting from cleavage adjacent to Y132. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human MMP15 at the amino acid range 113-162 |
Description
| Post Translational Modifications | The precursor is cleaved by a furin endopeptidase. |
| Function | Endopeptidase that degrades various components of the extracellular matrix. May activate progelatinase A. |
| Protein Name | Matrix Metalloproteinase-15Mmp-15Membrane-Type Matrix Metalloproteinase 2Mt-Mmp 2Mtmmp2Membrane-Type-2 Matrix MetalloproteinaseMt2-MmpMt2mmpSmcp-2 |
| Database Links | Reactome: R-HSA-1442490Reactome: R-HSA-1474228Reactome: R-HSA-1592389 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane ProteinExtracellular Side |
| Alternative Antibody Names | Anti-Matrix Metalloproteinase-15 antibodyAnti-Mmp-15 antibodyAnti-Membrane-Type Matrix Metalloproteinase 2 antibodyAnti-Mt-Mmp 2 antibodyAnti-Mtmmp2 antibodyAnti-Membrane-Type-2 Matrix Metalloproteinase antibodyAnti-Mt2-Mmp antibodyAnti-Mt2mmp antibodyAnti-Smcp-2 antibodyAnti-MMP15 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance