General Info
Host: | Rabbit |
Applications: | WB/IHC |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit monoclonal antibody anti-FGF21 (29-209) is suitable for use in Western Blot and Immunohistochemistry research applications. |
Clonality: | Monoclonal |
Clone ID: | S7MR |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH7.3. |
Purification: | Affinity purification |
Dilution Range: | WB 1:1000-1:5000IHC-P 1:50-1:200 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Information
Gene Symbol: | FGF21 |
Gene ID: | 26291 |
Uniprot ID: | FGF21_HUMAN |
Immunogen Region: | 29-209 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 29-209 of human FGF21 (NP_061986.1). |
Immunogen Sequence: | HPIPDSSPLLQFGGQVRQRY LYTDDAQQTEAHLEIREDGT VGGAADQSPESLLQLKALKP GVIQILGVKTSRFLCQRPDG ALYGSLHFDPEACSFRELLL EDGYNVYQSEAHGLPLHLPG NKSPHRDPAPRGPARFLPLP GLPPALPEPPGILAPQPPDV GSSDPLSMVGPSQGRSPSYA S |
Description
Function | Stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1 expression (but not SLC2A4/GLUT4 expression). Activity requires the presence of KLB. Regulates systemic glucose homeostasis and insulin sensitivity. |
Protein Name | Fibroblast Growth Factor 21Fgf-21 |
Database Links | Reactome: R-HSA-189200Reactome: R-HSA-8963889 |
Cellular Localisation | Secreted |
Alternative Antibody Names | Anti-Fibroblast Growth Factor 21 antibodyAnti-Fgf-21 antibodyAnti-FGF21 antibodyAnti-UNQ3115 antibodyAnti-PRO10196 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance