General Info
| Host: | Rabbit |
| Applications: | ELISA/IP/WB |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit polyclonal antibody anti-RNase H1 (240-286) is suitable for use in ELISA, Immunoprecipitation and Western Blot research applications. |
| Clonality: | Polyclonal |
| Conjugation: | FITC |
| Isotype: | IgG |
| Purification: | Affinity Purified |
| Concentration: | 0.5-1.5 Mu g/Mu l |
| Dilution Range: | WB: 1:500ELISA: 1:10, 000IP: 1:200 |
| Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Information
| Gene Symbol: | RNASEH1 |
| Gene ID: | 246243 |
| Uniprot ID: | RNH1_HUMAN |
| Immunogen Region: | 240-286 |
| Immunogen: | Synthetic peptide corresponding to amino acids within region 240-286 on human Rnase H1 protein. |
Description
| Function | Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. Plays a role in RNA polymerase II (RNAp II) transcription termination by degrading R-loop RNA-DNA hybrid formation at G-rich pause sites located downstream of the poly(A) site and behind the elongating RNAp II. |
| Protein Name | Ribonuclease H1Rnase H1Ribonuclease H Type Ii |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Ribonuclease H1 antibodyAnti-Rnase H1 antibodyAnti-Ribonuclease H Type Ii antibodyAnti-RNASEH1 antibodyAnti-RNH1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance