Bestrophin 4 Polyclonal Antibody, PE-Cy7 Conjugated

Cat# bs-11043R-PE-Cy7

Size : 100ul

Marca : Bioss

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Bestrophin 4 Polyclonal Antibody, PE-Cy7 Conjugated

Applications

  • WB

Reactivity

  • Human

Predicted Reactivity

  • Dog
  • Cow
  • Sheep
  • Pig
  • Horse
  • Rabbit
Overview
Catalog # bs-11043r-pe-cy7-100ul
Product Name Bestrophin 4 Polyclonal Antibody, PE-Cy7 Conjugated
Applications WB
Reactivity Human
Predicted Reactivity Dog, Cow, Sheep, Pig, Horse, Rabbit
Specifications
Conjugation PE-Cy7
Host Rabbit
Source KLH conjugated synthetic peptide derived from human Bestrophin 4
Immunogen Range 151-250/473
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Subcellular location Cell membrane
Synonyms BEST 4; BEST4; BEST-4; Bestrophin 4; Bestrophin4; Bestrophin-4; Vitellorm macular dystrophy 2 like 2; Vitellorm macular dystrophy 2 like protein 2; VMD2L2; BEST4_HUMAN.
Background Bestrophin-4 is a 473 amino acid member of the Bestrophin family of proteins. Members of the Bestrophin family are transmembrane proteins that contain a high percentage of aromatic residues, a conserved RFP (Arg-Phe-Pro) motif and they function as anion channels. Bestrophin-4 acts as a calcium-sensitive chloride channel located in the cell membrane. It is believed that Bestrophin-4 also acts as a channel for other physiologically significant anions, such as bicarbonate. Bestrophin-4 is predominantly expressed in the colon, but can be found at low levels in testis, placenta, trachea, spinal chord, lung and retina.
Application Dilution
WB 1:300-5000