Human Calpain 1 (CAPN1) activation kit by CRISPRa

Cat# GA100576

Size : 1kit

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Human Calpain 1 (CAPN1) activation kit by CRISPRa

Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol CAPN1
Locus ID 823
Components

GA100576G1, Calpain 1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA100576G2, Calpain 1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA100576G3, Calpain 1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001198868, NM_001198869, NM_001198870, NM_005186, NR_040008
UniProt ID P07384
Synonyms CANP; CANP1; CANPL1; muCANP; muCL; SPG76
Summary The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 1. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]
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SKU Description Size
KN400964 CAPN1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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