Human CD249 (ENPEP) protein (Recombinant)

Conjugation:	Unconjugated
Formulation:	0.2 Mu m filtered PBS solution, pH7.2.
Storage Instruction:	Can be stored in working aliquots at 2°C-8°C C for one month, or at-20°C to-70°C for 1 year. Avoid repeated freeze/thaw cycles. NA
Endotoxin:	Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg). NA

Gene Symbol:	ENPEP
Gene ID:	2028
Uniprot ID:	AMPE_HUMAN
Immunogen Region:	ECD
Immunogen:	Optimized DNA sequence encoding Human extracellular domain of human CD249including a C-terminal 6His tag was expressed in HEK293 cells. NA

Tissue Specificity	Expressed in choriocarcinoma cancer cell lines (at protein level). Expressed by epithelial cells of the proximal tubule cells and the glomerulus of the nephron. Also found in a variety of other tissues.
Function	Regulates central hypertension through its calcium-modulated preference to cleave N-terminal acidic residues from peptides such as angiotensin II.
Protein Name	Glutamyl Aminopeptidase Eap Aminopeptidase A Ap-A Differentiation Antigen Gp160 Cd Antigen Cd249
Database Links	Reactome: R-HSA-2022377
Cellular Localisation	Cell Membrane Single-Pass Type Ii Membrane Protein
Alternative Protein Names	Glutamyl Aminopeptidase protein Eap protein Aminopeptidase A protein Ap-A protein Differentiation Antigen Gp160 protein Cd Antigen Cd249 protein ENPEP protein

Information sourced from Uniprot.org

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