Human NDRG2 (N-myc Downstream Regulated Gene 2) Sandwich ELISA Kit Ready-To-Use

Storage Instruction:	The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:	3 hrs

Gene Symbol:	NDRG2
Gene ID:	57447
Uniprot ID:	NDRG2_HUMAN
Immunogen Region:	Ready-To-Use
Sample Type:	tissue homogenates or other biological fluids.

Tissue Specificity	Highly expressed in brain, heart, skeletal muscle and salivary gland, and moderately in kidney and liver. Expressed in dendritic cells, but not in other blood cells. Expression levels are low in pancreatic and liver cancer tissues.absent in meningioma. Expressed in low-grade gliomas but present at low levels in glioblastoma. Isoform 1 and isoform 2 are present in brain neurons and up-regulated in Alzheimer disease (at protein level).
Post Translational Modifications
Function	Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes, such as CCND1, and may thereby act as tumor suppressor. May be involved in dendritic cell and neuron differentiation.
Protein Name	Protein Ndrg2 N-Myc Downstream-Regulated Gene 2 Protein Protein Syld709613
Database Links
Cellular Localisation	Cytoplasm Perinuclear Region Cell Projection Growth Cone In Neurons Seems To Concentrate At Axonal Growth Cone Perinuclear In Neurons
Alternative ELISA Names	Protein Ndrg2 ELISA kit N-Myc Downstream-Regulated Gene 2 Protein ELISA kit Protein Syld709613 ELISA kit NDRG2 ELISA kit KIAA1248 ELISA kit SYLD ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance