Lipoteichoic Acid, mAb 55
Cat# HM5018-20UG
Size : 20ug
Marca : Hycult Biotech
Contatta il distributore locale :
Telefono : +1 850 650 7790
Lipoteichoic acid, mAb 55
The monoclonal antibody 55 recognizes lipoteichoic acid (LTA). LTA, a glycerol phosphate surface polymer, is a component of the envelope of Gram-positive bacteria. LTA is anchored via its glycolipids to the membrane and carries a polysaccharide chain extending into the peptidoglycan layer of the cell wall. LTA is released spontaneously into the culture medium during growth of gram-positive bacteria. LTA functions as an immune activator with characteristics very similar to lipopolysaccharide (LPS) from Gram-negative bacteria. LTA binds to CD14 and triggers activation predominantly via Toll-like receptor 2. Although LTA is internalized and traffics to the Golgi, the cellular activation in response to LTA occurs at the cell surface.
IF: 60' in PBS/0.02%BSA/0.02% saponin (ref 4)
W: A reduced or native sample treatment and run on 15% SDS-Page. Blot was incubated o/n at 4 °C with a 1/1000 dilution .The band size is ~17 kDa (Ref.6,7).
