General Info
Applications: | ELISA |
Reactivity: | Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: | 0.057ng/mL |
Detection Limit: | 0.156-10ng/mL |
Short Description: | This ALDOB Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: | 4.5 hrs |
Information
Gene Symbol: | Aldob |
Gene ID: | 230163 |
Uniprot ID: | ALDOB_MOUSE |
Sample Type: | serum, plasma or other biological fluids. |
Description
Tissue Specificity | |
Post Translational Modifications | |
Function | Catalyzes the aldol cleavage of fructose 1,6-biphosphate to form two triosephosphates dihydroxyacetone phosphate and D-glyceraldehyde 3-phosphate in glycolysis as well as the reverse stereospecific aldol addition reaction in gluconeogenesis. In fructolysis, metabolizes fructose 1-phosphate derived from the phosphorylation of dietary fructose by fructokinase into dihydroxyacetone phosphate and D-glyceraldehyde. Acts as an adapter independently of its enzymatic activity, exerts a tumor suppressor role by stabilizing the ternary complex with G6PD and TP53 to inhibit G6PD activity and keep oxidative pentose phosphate metabolism in check. |
Protein Name | Fructose-Bisphosphate Aldolase BAldolase 2Liver-Type Aldolase |
Database Links | Reactome: R-MMU-70171Reactome: -MMU-70263Reactome: -MMU-70350 |
Cellular Localisation | CytoplasmCytosolCytoskeletonMicrotubule Organizing CenterCentrosomeCentriolar Satellite |
Alternative ELISA Names | Fructose-Bisphosphate Aldolase B ELISA kitAldolase 2 ELISA kitLiver-Type Aldolase ELISA kitAldob ELISA kitAldo2 ELISA kit |
output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance