Mouse Anti-Bcl-xL-PE
Cat# 10030-09
Size : 0.1mg
Marca : Southern Biotech
Contatta il distributore locale :
Telefono : +1 850 650 7790
| Clone | 7B2.5 |
|---|---|
| Isotype | Mouse (BALB/c) IgG3κ |
| Isotype Control | Mouse IgG3-PE (B10) |
| Specificity | Human/Mouse/Rat/Rhesus Bcl-xL |
| Alternative Names | Apoptosis regulator Bcl-X, Bcl-2-like 1 protein, BCL2L1 |
| Description | Bcl-xL is a 29 kDa member of the Bcl-2 family of proteins involved in regulation of programmed cell death, or apoptosis. It is found in both soluble and membrane fractions of cellular lysates. Like Bcl-2, Bcl-xL has been demonstrated to block apoptosis which is induced by a variety of stimuli and, under certain conditions, offers greater protection against apoptosis than Bcl-2. While formation of heterodimers with the apoptosis-enhancing protein Bax does not block the apoptosis-suppressing property of Bcl-xL, heterodimerization with Bad effectively inhibits the protective function of Bcl-xL. |
| Immunogen | Recombinant human Bcl-xS |
| Conjugate | PE (R-phycoerythrin) |
| Buffer Formulation | Phosphate buffered saline containing < 0.1% sodium azide and a stabilizer |
| Clonality | Monoclonal |
| Concentration | 0.1 mg/mL |
| Volume | 1.0 mL |
| Recommended Storage | 2-8°C; Avoid exposure to light; Do not freeze |
| Applications | Flow Cytometry – Quality tested 2-25 Immunohistochemistry-Paraffin Sections – Reported in literature 26 Immunocytochemistry – Reported in literature 27 Western Blot – Reported in literature 1,28-30 Immunoprecipitation – Reported in literature 30,31 ELISA – Reported in literature 1 |
| RRID Number | AB_2794104 |
| Gene ID | 598 (Human) 12048 (Mouse) 24888 (Rat) 713035 (Rhesus) |
| Gene ID Symbol | BCL2L1 (Human) Bcl2l1 (Mouse) Bcl2l1 (Rat) BCL2L1 (Rhesus) |
| Gene ID Aliases | BCL-XL/S; BCL2L; BCLX; Bcl-X; PPP1R52; Bcl(X)L; Bcl-XL; Bcl2l; BclX; bcl-x; bcl2-L-1; Bcl-xl; Bclx; bcl-X; EGK_02534 |
| UniProt ID | Q07817 (Human Q64373 (Mouse P53563 (Rat |
| UniProt Name | B2CL1_HUMAN (Human) B2CL1_MOUSE (Mouse) B2CL1_RAT (Rat) |
Documentation
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