CD20 Unconjugated
Catalog #
Size
Lymphocytes gated cells stained with purified CD20 (clone 2H7) followed by donkey anti-mouse IgG iFluor488 (red histogram). Lymphocytes gated cells stained with purified mouse IgG2b isotype control followed by donkey anti-mouse IgG iFluor488 (Blue histogram).
| Conjugation | Unconjugated |
|---|---|
| Antigen | CD20 |
| Clone | 2H7 |
| Isotype | IgG2b, k |
| Applications | FC |
| Reactivity | Baboon, Cynomolgus monkey, Human, Rhesus |
| Host | Mouse |
| Clonality | Monoclonal |
| Primary/Secondary | Primary |
| Storage | 2-8°C |
| Status | RUO |
Description:
CD20, a 33-36 kDa non-glycosylated type 1 transmembrane protein, is expressed by developing, resting and mature B cells, some follicular dendritic cells, and a small subset of mature T cells. B cell CD20 expression is lost upon differentiation into plasma cells. Functionally, CD20 activation contributes to B cell activation, proliferation, and differentiation.
CD20, a 33-36 kDa non-glycosylated type 1 transmembrane protein, is expressed by developing, resting and mature B cells, some follicular dendritic cells, and a small subset of mature T cells. B cell CD20 expression is lost upon differentiation into plasma cells. Functionally, CD20 activation contributes to B cell activation, proliferation, and differentiation.