Mouse Anti-Chicken MHC Class II-PE
Cat# 8350-09
Size : 0.1mg
Marca : Southern Biotech
Contatta il distributore locale :
Telefono : +1 850 650 7790
| Clone | 2G11 |
|---|---|
| Isotype | Mouse IgG1κ |
| Isotype Control | Mouse IgG1-PE (15H6) |
| Specificity | Chicken/Pigeon/Caiman MHC class II β-chain |
| Alternative Names | B-L |
| Description | The chicken major histocompatibility complex (MHC), or B complex, consists of several clusters of highly polymorphic genes. Like their mammalian counterparts, the avian MHC exerts genetic influence over a variety of important biological functions such as immune response, disease resistance, growth and development, aging, and reproduction. Chicken MHC Class II genes, also known as the B-L subregion, of the chicken MHC encode cell surface glycoproteins that are homologous to mammalian Class II antigens. B-L antigens are structurally similar to mammalian Class II molecules in that they are noncovalently bound dimers of one heavy chain and one light chain. MHC Class II is primarily expressed on B cells and antigen presenting cells (APCs). |
| Conjugate | PE (R-phycoerythrin) |
| Buffer Formulation | Phosphate buffered saline containing < 0.1% sodium azide and a stabilizer |
| Clonality | Monoclonal |
| Concentration | 0.1 mg/mL |
| Volume | 1.0 mL |
| Recommended Storage | 2-8°C; Avoid exposure to light; Do not freeze |
| Applications | Flow Cytometry – Quality tested 1,4,6-19 Immunohistochemistry-Frozen Sections – Reported in literature 1,4,20 Electron Microscopy – Reported in literature 5 Immunoprecipitation – Reported in literature 1,2 Purification – Reported in literature 3 |
| RRID Number | AB_2796515 |
| Gene ID | 693256 (Chicken) 101747454 (Chicken) |
| Gene ID Symbol | BLB1 (Chicken) BLB2 (Chicken) |
| Gene ID Aliases | B-LB; B-LB21; GSP-BLB1; B-L; B-LB2; B-LBII; GSP-BLB2; S19 |
Documentation
Technical Bulletin Safety Datasheet
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- 1. Salomonsen J, Dunon D, Skjødt K, Thorpe D, Vainio O, Kaufman J. Chicken major histocompatibility complex-encoded B-G antigens are found on many cell types that are important for the immune system. Proc Natl Acad Sci USA. 1991;88:1359-63. (IP, IHC-FS, FC)
- 2. Kaufman J, Skjoedt K, Salomonsen J, Simonsen M, Du Pasquier L, Parisot R, et al. MHC-like molecules in some nonmammalian vertebrates can be detected by some cross-reactive xenoantisera. J Immunol. 1990;144:2258-72. (IP, Caiman Reactivity)
- 3. Salomonsen J, Marston D, Avila D, Bumstead N, Johansson B, Juul-Madsen H, et al. The properties of the single chicken MHC classical class II α chain (B-LA) gene indicate an ancient origin for the DR/E-like isotype of class II molecules. Immunogenetics. 2003;55:605-14. (Purification)
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