Mouse Anti-Human CD79b-BIOT

Cat# 9710-08

Size : 100tests

Marca : Southern Biotech

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Telefono : +1 850 650 7790

More Information
Clone CB3-1
Isotype Mouse (BALB/c) IgG1κ
Isotype Control Mouse IgG1-BIOT (15H6)
Specificity Human CD79b
Alternative Names B29, Igβ
Description CD79 is a disulfide-linked heterodimer composed of an α chain (CD79a) and a β chain (CD79b) that associates non-covalently with membrane immunoglobulin to form the B cell receptor (BCR) complex. Its expression is restricted to B lymphocytes first appearing on the surface at the pro-B cell stage and remaining through all stages of B cell differentiation prior to plasma cells. Crosslinking of the BCR leads to B cell activation. The monoclonal antibody CB3-1 reacts with the β chain of CD79.
Immunogen Ramos B cells
Conjugate BIOT (Biotin)
Buffer Formulation Phosphate buffered saline containing < 0.1% sodium azide
Clonality Monoclonal
Concentration Lot specific
Volume 1.0 mL
Recommended Storage 2-8°C
Applications Flow Cytometry – Quality tested 1,3-5
Immunoprecipitation – Reported in literature 1,2
Western Blot – Reported in literature 1

RRID Number AB_2797069
Gene ID 974 (Human)
Gene ID Symbol CD79B (Human)
Gene ID Aliases AGM6; B29; IGB
UniProt ID P40259 (Human
UniProt Name CD79B_HUMAN (Human)
Documentation
Technical Bulletin Safety Datasheet

Certificate of Analysis Lookup

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  1. 1. Nakamura T, Kubagawa H, Cooper MD. Heterogeneity of immunoglobulin-associated molecules on human B cells identified by monoclonal antibodies. Proc Natl Acad Sci USA. 1992;89:8522-6. (Immunogen, IP, WB, FC)
  2. 2. Lévéille C, Castaigne J, Charron D, Al-Daccak R. MHC class II isotype-specific signaling complex on human B cells. Eur J Immunol. 2002;32:2282-91. (IP)
  3. 3. Lanvin O, Guglielmi P, Fuentes V, Gouilleux-Gruart V, Mazière C, Bissac E, et al. TGF-β1 modulates Fas (APO-1/CD95)-mediated apoptosis of human pre-B cell lines. Eur J Immunol. 2003;33:1372-81. (FC)
  4. 4. Demurtas A, Stacchini A, Aliberti S, Chiusa L, Chiarle R, Novero D. Tissue flow cytometry immunophenotyping in the diagnosis and classification of non-Hodgkin's lymphomas: a retrospective evaluation of 1,792 cases. Cytometry B Clin Cytom. 2013;84B:82-95. (FC)
  5. 5. Stacchini A, Aliberti S, Pacchioni D, Demurtas A, Isolato G, Gazzera C, et al. Flow cytometry significantly improves the diagnostic value of fine needle aspiration cytology of lymphoproliferative lesions of salivary glands. Cytopathology. 2014;25:231-40. (FC)