Mouse Anti-Human Tollip-UNLB
Cat# 12060-01
Size : 0.1mg
Marca : Southern Biotech
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Telefono : +1 850 650 7790
| Clone | SB40a |
|---|---|
| Isotype | Mouse (BALB/c) IgG2aκ |
| Isotype Control | Mouse IgG2a-UNLB (HOPC-1) |
| Specificity | Human Tollip |
| Alternative Names | Toll interacting protein, IL-1RAcPIP |
| Description | Tollip, also known as Toll interacting protein, is a 30 kDa ubiquitin-binding protein that is a component of the signaling pathway of IL-1 and Toll-like receptors. It performs multiple functions and is classified as an adaptor protein. Tollip interacts with IRAK-1 (IL-1 receptor-associated kinase 1) prior to IL-1β stimulation and suppresses the kinase activity of IRAK-1. Tollip also associates with Tom1 forming a complex which regulates endosomal trafficking of ubiquitinated proteins. |
| Immunogen | Recombinant full length Tollip |
| Conjugate | UNLB (Unconjugated) |
| Buffer Formulation | Borate buffered saline, pH 8.2 |
| Clonality | Monoclonal |
| Concentration | 0.5 mg/mL |
| Volume | 0.2 mL |
| Recommended Storage | 2-8°C |
| Applications | Flow Cytometry – Quality tested 1 Western Blot 2 ELISA 2 |
| RRID Number | AB_2794709 |
| Gene ID | 54472 (Human) |
| Gene ID Symbol | TOLLIP (Human) |
| Gene ID Aliases | IL-1RAcPIP |
| UniProt ID | Q9H0E2 (Human |
| UniProt Name | TOLIP_HUMAN (Human) |
Documentation
Technical Bulletin Safety Datasheet
Certificate of Analysis Lookup
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- 1. Blok DC, Kager LM, Hoogendijk AJ, Lede IO, Rahman W, Afroz R, et al. Expression of inhibitory regulators of innate immunity in patients with active tuberculosis. BMC Infect Dis. 2015;15:98. (FC)
- 2. SouthernBiotech unpublished data (WB, ELISA)