General Info
Applications: | ELISA |
Reactivity: | Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: | 0.049ng/mL |
Detection Limit: | 0.156-10ng/mL |
Short Description: | This ITPA Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: | 4.5 hrs |
Information
Gene Symbol: | Itpa |
Gene ID: | 16434 |
Uniprot ID: | ITPA_MOUSE |
Sample Type: | tissue homogenates, cell lysates or other biological fluids. |
Description
Tissue Specificity | |
Post Translational Modifications | |
Function | Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triphosphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. |
Protein Name | Inosine Triphosphate PyrophosphataseItpaseInosine TriphosphataseNon-Canonical Purine Ntp PyrophosphataseNon-Standard Purine Ntp PyrophosphataseNucleoside-Triphosphate DiphosphataseNucleoside-Triphosphate PyrophosphataseNtpase |
Database Links | Reactome: R-MMU-74259Reactome: -MMU-9755088 |
Cellular Localisation | Cytoplasm |
Alternative ELISA Names | Inosine Triphosphate Pyrophosphatase ELISA kitItpase ELISA kitInosine Triphosphatase ELISA kitNon-Canonical Purine Ntp Pyrophosphatase ELISA kitNon-Standard Purine Ntp Pyrophosphatase ELISA kitNucleoside-Triphosphate Diphosphatase ELISA kitNucleoside-Triphosphate Pyrophosphatase ELISA kitNtpase ELISA kitItpa ELISA kit |
output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance