Clinisciences > NFKB1 Antibody - N-terminal region : HRP
NFKB1 Antibody - N-terminal region : HRP
Marca : Aviva Systems Biology
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Datasheets/Manuals | Printable datasheet for anti-NFKB1 (ARP38413_P050) antibody |
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Tested Species Reactivity | Human, Chicken |
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Predicted Species Reactivity | Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish, Chicken |
Product Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Clonality | Polyclonal |
Host | Rabbit |
Application | IHC, WB |
Reconstitution and Storage | For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Immunogen | The immunogen is a synthetic peptide directed towards the N terminal region of human NFKB1 |
Purification | Affinity Purified |
Predicted Homology Based on Immunogen Sequence | Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Zebrafish: 86% |
Peptide Sequence | Synthetic peptide located within the following region: PEQMFHLDPSLTHTIFNPEVFQPQMALPTDGPYLQILEQPKQRGFRFRYV |
Concentration | 0.5 mg/ml |
Blocking Peptide | For anti-NFKB1 (ARP38413_P050) antibody is Catalog # AAP38413 (Previous Catalog # AAPP20603) |
Reference | Heinemann,S., et al., (2006) J. Biol. Chem. 281 (13), 8565-8572 |
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Gene Symbol | NFKB1 |
Gene Full Name | Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 |
Alias Symbols | KBF1, EBP-1, NF-kB, CVID12, NF-kB1, NFKB-p50, NFkappaB, NF-kappaB, NFKB-p105, NF-kappa-B1, NF-kappabeta |
NCBI Gene Id | 4790 |
Protein Name | Nuclear factor NF-kappa-B p105 subunit |
Description of Target | NFKB1 is a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B |
Uniprot ID | P19838 |
Protein Accession # | NP_003989 |
Nucleotide Accession # | NM_003998 |
Protein Size (# AA) | 969 |
Molecular Weight | 105kDa |
Protein Interactions | FBXW11; UBC; RELB; RELA; REL; NFKB2; HDAC1; BCL3; NFKB1; RPS3; HIF1AN; NFKBIA; MPP6; PELP1; PLD3; MXD3; IKBKG; RL2; TP63; SRF; MAP3K8; PML; SERPINA3; SPPL2A; TNIP2; NFKBIZ; COPS5; YWHAQ; RGS14; NR4A1; GLUL; ABCC2; TNIP1; COPB2; YY1; PARP1; RPS6KA5; BTRC; |
Protein interactions
Name | # of Products |
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ANXA4 | 12 |
BANP | 13 |
BCL3 | 87 |
BRMS1 | 28 |
BTRC | 289 |
CARM1 | 120 |
CDK9 | 249 |
CLU | 87 |
DPF2 | 62 |
EP300 | 986 |
FBXW1 | 12 |
Gag-pol | 49 |
HDAC1 | 928 |
HDAC2 | 549 |
HDAC3 | 422 |
HDAC4 | 233 |
HDAC5 | 906 |
HMGA1 | 91 |
ITGB3BP | 63 |
MEN1 | 81 |
MTPN | 21 |
NCOA3 | 285 |
NCOR2 | 298 |
NFKBIA | 240 |
NFKBIZ | 30 |
NR3C1 | 215 |
PARP1 | 255 |
PCBD1 | 87 |
PDCD11 | 11 |
POLR2A | 376 |
PPME1 | 15 |
PSMD10 | 48 |
RELA | 381 |
RPS3 | 57 |
RSF1 | 16 |
SF1 | 69 |
SP1 | 551 |
SPAG9 | 33 |
SUMO1 | 972 |
Tat | 632 |
TNIP2 | 34 |
UNC5CL | 10 |
ZBTB9 | 49 |
ZFP36 | 30 |
Biological process
Name | # of Products |
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Anti-apoptosis | 239 |
Apoptotic process | 586 |
Cellular response to interleukin-1 | 32 |
Cellular response to mechanical stimulus | 62 |
Inflammatory response | 339 |
Innate immune response | 300 |
Membrane protein intracellular domain proteolysis | 12 |
MyD88-dependent toll-like receptor signaling pathway | 65 |
MyD88-independent toll-like receptor signaling pathway | 56 |
Negative regulation of calcidiol 1-monooxygenase activity | 3 |
Negative regulation of cellular protein metabolic process | 5 |
Negative regulation of cholesterol transport | 4 |
Negative regulation of transcription from RNA polymerase II promoter | 574 |
Negative regulation of vitamin D biosynthetic process | 4 |
Nerve growth factor receptor signaling pathway | 173 |
Positive regulation of canonical Wnt receptor signaling pathway | 50 |
Positive regulation of lipid storage | 5 |
Positive regulation of macrophage derived foam cell differentiation | 24 |
Positive regulation of NF-kappaB transcription factor activity | 135 |
Positive regulation of transcription, DNA-dependent | 681 |
Signal transduction | 1058 |
T cell receptor signaling pathway | 90 |
Toll signaling pathway | 66 |
Toll-like receptor 1 signaling pathway | 59 |
Toll-like receptor 2 signaling pathway | 61 |
Toll-like receptor 3 signaling pathway | 54 |
Toll-like receptor 4 signaling pathway | 64 |
Toll-like receptor signaling pathway | 71 |
Transcription from RNA polymerase II promoter | 302 |
TRIF-dependent toll-like receptor signaling pathway | 53 |
Cellular components
Name | # of Products |
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Cytoplasm | 4549 |
Cytosol | 1868 |
I-kappaB/NF-kappaB complex | 2 |
Mitochondrion | 1154 |
Nucleolus | 1179 |
Nucleoplasm | 775 |
Nucleus | 4914 |
Protein function
Name | # of Products |
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Enzyme binding | 898 |
Nucleic acid binding transcription factor activity | 27 |
Protein binding | 12191 |
Regulatory region DNA binding | 77 |
Sequence-specific DNA binding transcription factor activity | 2776 |
Transcription regulatory region DNA binding | 657 |
- NFKB1 ELISA Kit (Mouse) : 96 Wells (OKEH01301)Catalog #: OKEH01301Application: ELISA-SandwichKit Range: 0.156-10ng/mLSensitivity: 0.091 ng/mLSize: 96T
- NFKB1 ELISA Kit (Human) (OKEH04591)Catalog #: OKEH04591Application: ELISA-SandwichKit Range: 0.312-20ng/mLSensitivity: 0.23 ng/mLSize: 96T