nNOS Ser1417 Polyclonal Antibody, HRP Conjugated
Cat# bs-19301R-HRP
Size : 100ul
Marca : Bioss
nNOS Ser1417 Polyclonal Antibody, HRP Conjugated
Applications
Reactivity
Predicted Reactivity
Overview | |
Catalog # | bs-19301R-HRP |
Product Name | nNOS Ser1417 Polyclonal Antibody, HRP Conjugated |
Applications | WB, ELISA, IHC-P, IHC-F |
Reactivity | Human, Rat, Xenopus laevis |
Predicted Reactivity | Mouse, Zebrafish |
Specifications | |
Conjugation | HRP |
Host | Rabbit |
Source | KLH conjugated Synthesised phosphopeptide derived from human nNOS around the phosphorylation site of Ser1417 |
Modification Site | Ser1417 |
Clonality | Polyclonal |
Isotype | IgG |
Concentration | 1ug/ul |
Purification | Purified by Protein A. |
Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Storage Condition | Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target | |
Gene ID | 842 |
Swiss Prot | P55211 |
Subcellular location | Cell membrane |
Synonyms | MCH6; APAF3; APAF-3; PPP1R56; ICE-LAP6; Caspase-9; CASP-9; Apoptotic protease Mch-6; Apoptotic protease-activating factor 3; ICE-like apoptotic protease 6; CASP9 |
Background | Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP). Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9. |
Application Dilution | |
WB | 1:300-5000 |
ELISA | 1:500-1000 |
IHC-P | 1:200-400 |
IHC-F | 1:100-500 |