nNOS Ser1417 Polyclonal Antibody, HRP Conjugated

Cat# bs-19301R-HRP

Size : 100ul

Marca : Bioss

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nNOS Ser1417 Polyclonal Antibody, HRP Conjugated

Applications

  • WB
  • ELISA
  • IHC-P
  • IHC-F

Reactivity

  • Human
  • Rat
  • Xenopus laevis

Predicted Reactivity

  • Mouse
  • Zebrafish
Overview
Catalog # bs-19301R-HRP
Product Name nNOS Ser1417 Polyclonal Antibody, HRP Conjugated
Applications WB, ELISA, IHC-P, IHC-F
Reactivity Human, Rat, Xenopus laevis
Predicted Reactivity Mouse, Zebrafish
Specifications
Conjugation HRP
Host Rabbit
Source KLH conjugated Synthesised phosphopeptide derived from human nNOS around the phosphorylation site of Ser1417
Modification Site Ser1417
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 842
Swiss Prot P55211
Subcellular location Cell membrane
Synonyms MCH6; APAF3; APAF-3; PPP1R56; ICE-LAP6; Caspase-9; CASP-9; Apoptotic protease Mch-6; Apoptotic protease-activating factor 3; ICE-like apoptotic protease 6; CASP9
Background Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP). Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.
Application Dilution
WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500