Prazosin hydrochloride
Cat# M5895-50mg
Size : 50mg
Marca : AbMole Bioscience
Contatta il distributore locale :
Telefono : +1 850 650 7790
All AbMole products are for research use only, cannot be used for human consumption.
cp-12299-1
Quality Control & Documentation
Biological Activity
Prazosin hydrochloride, a Quinazoline derivative, is a well-tolerated, CNS-active α1-adrenergic receptor antagonist for the research of high blood pressure and alcohol use disorders. Prazosin hydrochloride potently inhibits Norepinephrine (NE)-stimulated 45Ca efflux with an IC50 of 0.15 nM. Prazosin hydrochloride inhibits organic cation transporters OCT-1 and OCT-3 with IC50s of 1.8, and 13 μM, respectively.
Chemical Information
| Molecular Weight | 419.86 |
| Formula | C19H21N5O4·HCl |
| CAS Number | 19237-84-4 |
| Solubility (25°C) | DMSO 7 mg/mL |
| Storage | Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
References
[1] Haagsman AN, et al. Vet Rec. Comparison of terazosin and prazosin for treatment of vesico-urethral reflex dyssynergia in dogs.