Prion Protein (PrP, Prnp, ASCR, Atal Familial Insomnia, CD230 Antigen, CJD, Creutzfeld Jakob Disease, Gerstmann-Strausler-Scheinker Syndrome, GSS, Major Prion Protein, MGC26679, Prion Related Protein, PRIP, Prni, PrP27-30, PrP33-35C, PrPC, PrPSc, Sinc) (Biotin)

Cat# P8950-26C-Biotin-100ul

Size : 100ul

Marca : US Biological

Richiedere ulteriori informazioni

Contatta il distributore locale :


Telefono : +1 850 650 7790


P8950-26C-Biotin Prion Protein (PrP, Prnp, ASCR, Atal Familial Insomnia, CD230 Antigen, CJD, Creutzfeld Jakob Disease, Gerstmann-Strausler-Scheinker Syndrome, GSS, Major Prion Protein, MGC26679, Prion Related Protein, PRIP, Prni, PrP27-30, PrP33-35C, PrPC, PrPSc, Sinc) (Biotin)

Clone Type
Polyclonal
Host
mouse
Source
sheep
Isotype
IgG2a
Grade
Affinity Purified
Applications
E IHC
Crossreactivity
Sh
Shipping Temp
Blue Ice
Storage Temp
-20°C

Applications:|Suitable for use in ELISA and Immunohistochemistry. Other applications not tested. ||Recommended Dilution:|Immunohistochemistry (paraffin): Requires antigen retrieval using heat treatment prior to staining of paraffin sections.|Optimal dilutions to be determined by the researcher. ||Storage and Stability:|Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.||Note: Applications are based on unconjugated antibody.

Applications
Product Type: Mab|Isotype: IgG2a|Clone No: 2G11|Host: mouse|Source: sheep|Concentration: As Reported|Form: Supplied as a liquid in PBS, pH 7.2. Labeled with Biotin.|Purity: Purified by Protein G affinity chromatography from tissue culture supernatant.|Immunogen: Synthetic peptide 146-R154R171-182 of sheep PrP.|Specificity: Recognizes sheep CD230 (PrPsc).||Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Immunogen
Synthetic peptide 146-R154R171-182 of sheep PrP.
Form
Supplied as a liquid in PBS, pH 7.2. Labeled with Biotin.
Purity
Purified by Protein G affinity chromatography from tissue culture supernatant.
Specificity
Recognizes sheep CD230 (PrPsc).
References
1. Andreoletti, O. et al. (2000) Early accumulation of PrP(Sc) in gut-associated lymphoid and nervous tissues of susceptible sheep from a Romanov flock with natural scrapie. J Gen Virol. 81: 3115-3126, 2. Andreoletti, O. et al. (2002) Phenotyping of protein-prion (PrPsc)-accumulating cells in lymphoid and neural tissues of naturally scrapie-affected sheep by double-labeling immunohistochemistry. J Histochem Cytochem.50:1357-70.