Pyruvate Dehydrogenase E1 alpha antibody

Cat# GTX104015-100ul

Size : 100ul

Marca : GeneTex

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Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, ICC/IF, IHC-P, IHC-Wm, IP, IHC (Free Floating)

Reactivity

Human, Mouse, Rat, Zebrafish
Package
100 μl,
25 μl
View product citations for antibody GTX104015 on CiteAb

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:10000
ICC/IF 1:100-1:1000
IHC-P 1:100-1:1000
IHC-Wm Assay dependent
IP 1:100-1:500
IHC (Free Floating) Assay dependent
Not tested in other applications.
Application Reference
CM MacLeod et al. PLoS One 2023; 18 (11):e0294312 Trehalose enhances mitochondria deficits in human NPC1 mutant fibroblasts but disrupts mouse Purkinje cell dendritic growth ex vivo
Kim S et al. Sci Rep 2023; 13 (1):5665 Disruptive lysosomal-metabolic signaling and neurodevelopmental deficits that precede Purkinje cell loss in a mouse model of Niemann-Pick Type-C disease.
Application : WB, IHC (Free Floating)
Reactivity : Mouse
Kirova DG et al. Dev Cell 2022; 57 (14):1712-1727.e9 A ROS-dependent mechanism promotes CDK2 phosphorylation to drive progression through S phase.
Marco Rosina et al. Cell Metab 2022; 34 (4):533-548.e12 Ejection of damaged mitochondria and their removal by macrophages ensure efficient thermogenesis in brown adipose tissue.
Application : WB
Reactivity : Mouse
Rey T et al. Nat Cell Biol 2020; 22 (10):1180-1186 Mitochondrial RNA granules are fluid condensates positioned by membrane dynamics.
Zhang R et al. Cell Death Dis 2020; 11 (10):885 Selective knockdown of hexokinase 2 in rods leads to age-related photoreceptor degeneration and retinal metabolic remodeling.
Jonus HC et al. Biomed Pharmacother 2020; 121:109648 Thiamine mimetics sulbutiamine and benfotiamine as a nutraceutical approach to anticancer therapy.
Application : WB
Reactivity : Human
Chen Y et al. J Biol Chem 2015; 290 (39):23826-37 Critical Role of the Neonatal Fc Receptor (FcRn) in the Pathogenic Action of Antimitochondrial Autoantibodies Synergizing with Anti-desmoglein Autoantibodies in Pemphigus Vulgaris.
Deng W et al. Endocrinology 2014; 155 (5):1618-28 Protein kinase B (PKB/AKT1) formed signaling complexes with mitochondrial proteins and prevented glycolytic energy dysfunction in cultured cardiomyocytes during ischemia-reperfusion injury.
BRADLEY SCOTT HANBERRY et al. 0 2014; TARGETING THE CANCER METABOLIC PHENOTYPE USING HIGH DOSE VITAMIN B1 THERAPY.
Application : WB
Reactivity : Human
Chao LC et al. J Lipid Res 2012; 53 (12):259567 Skeletal muscle Nur77 expression enhances oxidative metabolism and substrate utilization.
SDS
PBS.pdf
Glycerol.pdf
Proclin.pdf

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