Rimantadine (hydrochloride) [1501-84-4]
Cat# HY-B0338A-100mg
Size : 100mg
Marca : MedChemExpress
Rimantadine hydrochloride is an anti-influenza virus drug.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
Rimantadine hydrochloride Chemical Structure
CAS No. : 1501-84-4
This product is a controlled substance and not for sale in your territory.
Description |
Rimantadine hydrochloride is an anti-influenza virus drug. Target: Influenza Virus Rimantadine hydrochloride are oral antiviral drugs useful in the prophylaxis and treatment of influenza A virus infections. rimantadine has prophylactic efficacy comparable to amantadine but lower potential for causing adverse effects [1]. double-blind study of children with influenza-like illness. 37 received rimantadine for five days. Of the total 37 children in the rimantadine group, 27% were found to have resistant isolated compared with 6% in the total group receiving acetaminophen (P < .04). Furthermore, the mean inhibitory concentration of rimantadine increased with time in the rimantadine group (r = .4, P = .002) [2]. |
||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Essai clinique |
|
||||||||||||
Masse moléculaire |
215.76 |
||||||||||||
Formule |
C12H22ClN |
||||||||||||
CAS No. |
1501-84-4 |
||||||||||||
Appearance |
Solid |
||||||||||||
Color |
White to off-white |
||||||||||||
SMILES |
CC(C1(C[C@H](C2)C3)C[C@H]3C[C@H]2C1)N.Cl |
||||||||||||
Livraison | Room temperature in continental US; may vary elsewhere. |
||||||||||||
Stockage |
4°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
||||||||||||
Solvant et solubilité |
In Vitro:
DMSO : 50 mg/mL (231.74 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO) H2O : 33.33 mg/mL (154.48 mM; Need ultrasonic) Preparing
Stock Solutions
View the Complete Stock Solution Preparation Table
*
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles. * Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol) Concentration (start) × Volume (start) = Concentration (final) × Volume (final) This equation is commonly abbreviated as: C1V1 = C2V2 In Vivo:
Select the appropriate dissolution method based on your experimental animal and administration route.
For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
For the following dissolution methods, please prepare the working solution directly.
It is recommended to prepare fresh solutions and use them promptly within a short period of time.
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
Dosage mg/kgAnimal weight Dosing volume Number of animals Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration:
mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
|
||||||||||||
Pureté et documentation |
Purity: ≥98.0% |
||||||||||||
Références |
|
Complete Stock Solution Preparation Table
*
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
---|
H2O / DMSO | 1 mM | 4.6348 mL | 23.1739 mL | 46.3478 mL | 115.8695 mL |
5 mM | 0.9270 mL | 4.6348 mL | 9.2696 mL | 23.1739 mL | |
10 mM | 0.4635 mL | 2.3174 mL | 4.6348 mL | 11.5869 mL | |
15 mM | 0.3090 mL | 1.5449 mL | 3.0899 mL | 7.7246 mL | |
20 mM | 0.2317 mL | 1.1587 mL | 2.3174 mL | 5.7935 mL | |
25 mM | 0.1854 mL | 0.9270 mL | 1.8539 mL | 4.6348 mL | |
30 mM | 0.1545 mL | 0.7725 mL | 1.5449 mL | 3.8623 mL | |
40 mM | 0.1159 mL | 0.5793 mL | 1.1587 mL | 2.8967 mL | |
50 mM | 0.0927 mL | 0.4635 mL | 0.9270 mL | 2.3174 mL | |
60 mM | 0.0772 mL | 0.3862 mL | 0.7725 mL | 1.9312 mL | |
80 mM | 0.0579 mL | 0.2897 mL | 0.5793 mL | 1.4484 mL | |
100 mM | 0.0463 mL | 0.2317 mL | 0.4635 mL | 1.1587 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.