SLC5A5 monoclonal antibody, clone FP5 (APC)
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Application Data with Unconjugated Antibody
Western Blot (Tissue lysate)
Western blot analysis of human retina lysate with SLC5A5 monoclonal antibody, clone FP5 (MAB11494) at 1:1000 dilution.
- Specifications
Product Description
Mouse monoclonal antibody raised against recombinant of SLC5A5.
Immunogen
Recombinant mannose fusion protien corresponding to amino acids 468-643 of human SLC5A5.
Host
Mouse
Reactivity
Human, Mouse, Rat
Specificity
Mapped to amino acids 625-643 of hNIS. Apparent mol. wt of 97 kD, non-glycosylated version at 68 kD. Other minor bands associated with hNIS at 160 kDa, and degradation products at ~30 kDa, and ~15kDa.
Form
Liquid
Conjugation
APC
Purification
Protein G purification
Isotype
IgG1, kappa
Recommend Usage
Immunofluorescence
Immunohistochemistry
Western blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (50% glycerol)
Storage Instruction
Store at 4°C.
Aliquot to avoid repeated freezing and thawing.Note
Application Data with Unconjugated Antibody
Western Blot (Tissue lysate)
Western blot analysis of human retina lysate with SLC5A5 monoclonal antibody, clone FP5 (MAB11494) at 1:1000 dilution.
- Applications
Western Blot
Immunohistochemistry
Immunofluorescence
- Gene Info — SLC5A5
Entrez GeneID
6528Protein Accession#
Q92911Gene Name
SLC5A5
Gene Alias
NIS
Gene Description
solute carrier family 5 (sodium iodide symporter), member 5
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the sodium glucose cotransporter family. The encoded protein is responsible for the uptake of iodine in tissues such as the thyroid and lactating breast tissue. The iodine taken up by the thyroid is incorporated into the metabolic regulators triiodothyronine (T3) and tetraiodothyronine (T4). Mutations in this gene are associated with thyroid dyshormonogenesis 1
Other Designations
sodium-iodide symporter
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