SPRR1a (Small Proline-Rich Repeat Protein 1A)

SPRR1A belongs to a multigene family consisting of two SPRR1 genes (SPRR1A and -1B), seven SPRR2 genes (SPRR2A to -2F), and one SPRR3 gene. These genes encode small molecular weight proteins exceptionally rich in proline, cysteine and glutamate and were first identified as inducible gene products in human keratinocytes. In addition to its expression in epithelial cells, SPRR1a is localized to injured neurons and axons and is induced in neurons by axotomy where it appears to promote axonal regeneration.||Sequence (linear): H-CPPTVTPSPYQQKTKQK-OH||Storage and Stability: |Lyophilized powder may be stored at 4°C for short-term only. Stable for 12 months at -20°C. Reconstitute to nominal volume (see reconstitution instructions for peptides) and store at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.|||