The skeletal system provides structural support, movement, protection, blood cell production, calcium storage and endocrine regulation of the body. The human skeletal system consists of an axial skeleton (surrounding the viscera) and an appendicular skeleton (upper and lower limbs), both attached to the medial axis (the spine) by the scapular and pelvic girdles. The bones are classified into three categories, according to their morphology: long bones, short bones and flat bones. They contain the bone marrow, the site of blood cell production. Abnormal cell regulation within the skeletal system can lead to the development of diseases such as osteoporosis, osteomalacia, scoliosis and bone cancer. We propose different types of normal human primary cells in the skeletal cell system, including: calvarial osteoblasts, femoral osteoblasts, articular chondrocytes, synoviocytes, nucleus pulposus cells and annulus fibrosus cells.
